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eliu joined: 2007-08-09 posted: 11480 promoted: 617 bookmarked: 187 新竹, 台灣 |
研究發現,維他命D&鈣 可以增加 Bax 這種可以調節細胞自發性死亡的蛋白質,對於癌症細胞的死亡很重要。E-cadherin 與細胞增生有關,服用維他命D&鈣的人E-cadherin 最低。 在一項雙盲、有安慰劑控制的實驗中,有零散直腸瘤的患者給予 維他命D及/或鈣,服用維他命D的人比安慰劑的人 Bax蛋白質增加 56%; 另外一項研究有關於 E-cadherin & beta-catenin的水平, beta-catenin 與 85% 的直腸癌有關。研究者發現同時服用維他命D&鈣 抑制 E-cadherin & beta-catenin 的效果最好,比只服用鈣或維他命D好。
Fedirko V, Bostick RM, Flanders WD, Long Q, Cohen V. Effect of vitamin D and calcium supplementation on markers of apoptosis in normal colon mucosa: Results from a randomized clinical trial. Abstract 464. Presented at the 2008 American Association for Cancer Research Annual Meeting, 13 April 2008, San Diego. Thomas A, Dash C, Bostick RM. Associations of calcium and vitamin D with E-cadherin and β-catenin expression in normal-appearing rectal tissue; markers of adenomatous polyps II (MAP II) case-control study. Abstract 565. Presented at the 2008 American Association for Cancer Research Annual Meeting, 13 April 2008, San Diego. |
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