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葡萄子萃取物 grape seed extract 可以抑制細菌 Porphyromonas gingivalis and Fusobacterium nucleatum，這兩種細菌會造成口臭及牙周病。 葡萄子萃取物 grape seed extract 也可以穿透細菌外層的保護膜。 葡萄子 grape seed extract 的抗氧化功能，可以減少造成發炎的活氧化物 reactive oxygen species。
Furiga A, Lonvaud-Funel A, Badet C. In vitro study of antioxidant capacity and antibacterial activity on oral anaerobes of a grape seed extract. Food Chemistry. 15 April 2009;113( 4);1037-1040. Available online prior to April publication date. edited: 1
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